diff --git a/axum-core/src/response/into_response.rs b/axum-core/src/response/into_response.rs
index ab684e2c..91355b69 100644
--- a/axum-core/src/response/into_response.rs
+++ b/axum-core/src/response/into_response.rs
@@ -190,6 +190,12 @@ impl IntoResponse for String {
     }
 }
 
+impl IntoResponse for Box<str> {
+    fn into_response(self) -> Response {
+        String::from(self).into_response()
+    }
+}
+
 impl IntoResponse for Cow<'static, str> {
     fn into_response(self) -> Response {
         let mut res = Body::from(self).into_response();
@@ -315,6 +321,12 @@ impl IntoResponse for Vec<u8> {
     }
 }
 
+impl IntoResponse for Box<[u8]> {
+    fn into_response(self) -> Response {
+        Vec::from(self).into_response()
+    }
+}
+
 impl IntoResponse for Cow<'static, [u8]> {
     fn into_response(self) -> Response {
         let mut res = Body::from(self).into_response();
diff --git a/axum/CHANGELOG.md b/axum/CHANGELOG.md
index 9697969a..9d5388d1 100644
--- a/axum/CHANGELOG.md
+++ b/axum/CHANGELOG.md
@@ -53,6 +53,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - **breaking:** Only inherit fallbacks for routers nested with `Router::nest`.
   Routers nested with `Router::nest_service` will no longer inherit fallbacks ([#1956])
 - **fixed:** Don't remove the `Sec-WebSocket-Key` header in `WebSocketUpgrade` ([#1972])
+- **added:** Implement `IntoResponse` for `Box<str>` and `Box<[u8]>` ([#2035])
 
 [#1664]: https://github.com/tokio-rs/axum/pull/1664
 [#1751]: https://github.com/tokio-rs/axum/pull/1751